* This product is for research use only. Not intended for use in the treatment or diagnosis of disease.
Gene therapy is a new technology that combines modern medicine and molecular biology by introducing the target gene into the patient and achieving the target gene product. Gene therapy as a new approach to disease treatment has already had some successful applications, and scientific breakthroughs will continue to push gene therapy into mainstream medicine.
Gene therapy can work through a variety of mechanisms:
A variety of vectors have been developed to carry the target genes into the body, these vectors can be injected directly or intravenously into specific tissues in the body, where it is taken up by individual cells. Alternatively, samples of patient cells can be taken in a laboratory setting and exposed to the carrier. Cells containing the vector are then returned to the patient. If the treatment is successful, the new gene delivered by the carrier will produce a functional protein, or the edited molecule will correct the DNA error and restore protein function.
Circular DNA molecules can be genetically engineered to carry therapeutic genes into human cells.
Viruses have the natural ability to deliver genetic material to cells, so some gene therapy products are derived from viruses (Retroviruses, adenoviruses, adeno-associated viruses, etc). Once a virus has been modified to eliminate its ability to cause infectious disease, these modified viruses can be used as vehicles to carry therapeutic genes into human cells.
Bacteria can be modified to prevent them from causing infectious diseases and then used as vehicles to carry therapeutic genes into human tissues.
|Catalog No.||Product Name||Description|
|BT-000001||DNA in vivo Delivery Kit||Reagents designed for plasmid DNA in vivo transfection.|
|BT-000044||siRNA/DNA Transfection Reagent||BOC Sciences siRNA/DNA transfection reagent is a highly efficient, low toxicity, ideal siRNA and plasmid DNA transfection reagent for mammalian cells.|
|BT-000030||DOTAP-Lipo Transfection Reagent||Reagents for DNA, RNA and protein transfection.|
|BT-000023||Broad Spectrum DNA Transfection Reagent||Reagents for DNA transfection.|
|BT-000046||CRISPR RNP Transfection Reagent||BOC Sciences' CRISPR RNP transfection reagent is a polymer-based transfection reagent with a membrane fusion virus mechanism that can efficiently deliver Cas9 ribonucleoprotein (RNP) in vitro.|
|BT-000005||Cas9 Transfection Reagent||Optimized lipid nanoparticle transfection reagent for CRISPR-Cas9 protein delivery|
|BT-000042||HTT mRNA Transfection Reagent||Reagents for high-efficiency delivery of mRNA into hard-to-transfect cells.|
|BT-000041||mRNA Transfection Reagent||Transfection reagent for mRNA.|
|BT-000043||siRNA Transfection Reagent||BOC Sciences' siRNA transfection reagent is an efficient, low toxicity, ideal siRNA transfection system for mammalian cells.|
|BT-000012||Hela CRISPR Transfection Reagent||Proprietary preparation reagent optimized for delivery of CRISPR/Cas9 gene modification system into Hela cells.|
|BT-000014||HepG2 CRISPR Transfection Reagent||Proprietary preparation reagent optimized for delivery of CRISPR/Cas9 gene modification system into HepG2 cell line.|
|BT-000022||Astrocytes Transfection Reagent||Reagents optimized for high-efficient delivery of DNA and RNA into Astrocyte cells.|
|BT-000021||Neuro-2a Transfection Reagent||Reagents designed for efficient delivery of DNA and RNA into neuroblastoma cells.|
|BT-000020||Neuro-Transfection Reagent||Reagents designed for high-efficient transfection of DNA into nerve cells.|