* This product is for research use only. Not intended for use in the treatment or diagnosis of disease.
|If stored properly, all components are stable for 6 months.
|Store at 4°C.
|Nanoparticle In Vivo Transfection Reagent is composed of nano-polymers. At physiological pH, the amino groups of nano-polymers are protonated. Thus, negative charges on the surface of DNA plasmids are neutralized by protonated amino groups, resulting in DNA molecular structures being compressed into relatively small DNA particles. Nanoparticles encapsulate small DNA particles and protect DNA from degradation by nucleases. The transfection complex transfers DNA into the cell through endocytosis, forming an endosome. Then DNA is released from the endosome and enters the cytoplasm to further transcribe and express in the nucleus. Transfection reagents produced by nanotechnology exhibit unique properties of high transfection efficiency and low toxicity at the nanoscale.
|Cells in vivo.
|Including nanoparticle-based in vivo transfection reagents and transfection enhancer reagents.
|Nanoparticle In Vivo Transfection Reagent is a newly developed and synthesized nanoparticle formulation with low toxicity and high efficiency; It is used for efficient transfection to optimized siRNA, shRNA, miRNA, and plasmid DNA in vivo delivery.
|No nuclease contamination and microbial contamination.
|Shipped at ambient temperature.
|For research use only; Not suitable for any diagnostic or therapeutic use.
|Reagents designed for siRNA, miRNA, DNA efficient transfection in vivo.