Nanoparticle In Vivo Transfection Reagent (BT-000050)

* This product is for research use only. Not intended for use in the treatment or diagnosis of disease.

Product Information
Catalog NumberBT-000050
Shelf LifeIf stored properly, all components are stable for 6 months.
StorageStore at 4°C.
Brief IntroductionNanoparticle In Vivo Transfection Reagent is composed of nano-polymers. At physiological pH, the amino groups of nano-polymers are protonated. Thus, negative charges on the surface of DNA plasmids are neutralized by protonated amino groups, resulting in DNA molecular structures being compressed into relatively small DNA particles. Nanoparticles encapsulate small DNA particles and protect DNA from degradation by nucleases. The transfection complex transfers DNA into the cell through endocytosis, forming an endosome. Then DNA is released from the endosome and enters the cytoplasm to further transcribe and express in the nucleus. Transfection reagents produced by nanotechnology exhibit unique properties of high transfection efficiency and low toxicity at the nanoscale.
Cell TypesCells in vivo.
  • Simplify tedious experimental steps and make operation easy.
  • Nanoparticles are biodegradable upon entry into cells.
  • Nanoparticles can easily enter cells to achieve high transfection rates.
  • Minimal toxicity, up to 95% cell survival rate after transfection.
  • Ultra-high specificity.
ContentsIncluding nanoparticle-based in vivo transfection reagents and transfection enhancer reagents.
DetailsNanoparticle In Vivo Transfection Reagent is a newly developed and synthesized nanoparticle formulation with low toxicity and high efficiency; It is used for efficient transfection to optimized siRNA, shRNA, miRNA, and plasmid DNA in vivo delivery.
IdentificationNo nuclease contamination and microbial contamination.
ShippingShipped at ambient temperature.
Use LimitationsFor research use only; Not suitable for any diagnostic or therapeutic use.
DescriptionReagents designed for siRNA, miRNA, DNA efficient transfection in vivo.
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